As part of the International Liver Congress (ILC) 2021, the EASL Takeaways take a look at key topics from the congress, with leading experts discussing the most impactful science and putting it into perspective. In this session, Professors Ana Lleo, Saskia van Mil and Ulrich Beuers cover the most newsworthy developments from three topics – autoimmune hepatitis (AIH), cholestatic liver diseases and rare hereditary liver diseases.
Professor Lleo first presents abstracts on key risk factors associated with AIH recurrence and the role of multiparametric MRI as a non-invasive tool to assess AIH disease activity, before the panel assess their clinical implications. The discussion then moves on to surveillance strategies for primary sclerosing cholangitis. Finally, Professor van Mil highlights abstracts on genotype-selected risk of liver disease and HCC in people with alpha-1 antitrypsin deficiency, and on the efficacy of GNT0003, a novel gene therapy for patients with Crigler-Najjar Syndrome.